The picture shows Chen Xin, a researcher at the School of Chemical Engineering of Xi'an Jiaotong University, explaining the research results. Dang Yeye
"The construction of intelligent controlled-release materials can successfully solve biomedical problems such as precise treatment of tumors, infectious diseases, immune diseases and other diseases, and efficient induction regeneration of bones, skin, teeth and other tissues." Chen Xin, a researcher at the School of Chemical Engineering, Xi'an Jiaotong University The Japanese said that this technology will also be used in beauty, heightening and other applications in the future.
It is understood that chemotherapy is one of the main means of treating cancer at present. Traditional chemotherapy is inefficient and accompanied by obvious toxic and side effects. The intelligent controlled release material is like an "alarm clock" that "controls the release of drugs", and controls whether or not it is released, the rate of release, and the degree of release based on the environmental response of the lesion. It has the advantages of being able to load a large amount of bioactive drugs, protecting the active ingredients of the drugs, improving the bioavailability of the drugs, and helping the drug targeting and positioning.
Chen Xin said that intelligent controlled-release materials are considered to be an important development direction in the field of modern biomedicine, and have received more and more attention in the fields of disease treatment and tissue regeneration. Due to the complexity and variability of clinical conditions, how to achieve precise drug delivery that fully meets physiological needs through intelligent controlled release materials is still a problem that puzzles clinical medicine.
Through the design and functionalization of nano drug carriers, the research team introduced advanced concepts such as chemotherapy, photothermal therapy, targeted therapy, and visual therapy into the treatment of oral cancer, and built a micro-nano device for intelligent tumor therapy, which achieved Effective treatment and precise labeling of oral cancer and other cancers, and long-term suppression of their recurrence, significantly improved the survival rate of patients.
According to reports, the team prepared a micro-nano composite scaffold with a bionic structure and a growth factor carrier to achieve complete repair of large-area non-return-shaped bone and skin defects. A tumor microenvironment-responsive nanocomposite scaffold is constructed, which can responsively release tumor-targeted nano-drug carriers around postoperative residual tumor cells, accurately kill tumor cells and inhibit tumor metastasis without affecting healthy cells.
The researchers said that the relevant design reduces the damage to the donor cells during the treatment process, so that the pre-loaded stem cells still have the differentiation and regeneration potential after tumor treatment, thereby achieving the integration of tumor treatment tissue regeneration.
"This technology is also very practical in life, which can make the mask better absorbed and increase bone growth." Chen Xin told reporters that the technology has been communicated with some companies and institutions in applications, covering medical and beauty , Health care and other fields. (Party Field)
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